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Reference #: 1006423
SHIFT:Day (United States of America)

Seeking Breakthrough Makers

Children's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care-and your career.

CHOP's Commitment to Diversity, Equity, and Inclusion

CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children.

We strongly encourage all candidates of diverse backgrounds and lived experiences to apply.

A Brief Overview
Dr. Sengupta is a neonatologist and physician scientist with a long-standing interest in lung health. She studies the mechanisms of circadian regulation of lung inflammation, injury, and repair; and the effect of early life exposures on development and function of pulmonary circadian networks in adulthood.

We are looking for a research technician for exciting work aimed at uncovering circadian underpinnings of lung injury. I am a physician scientist and an Assistant Professor of Pediatrics and we have many novel and interesting projects at various stages of development.

Potential candidates will be expected to carry out basic molecular and cellular biology procedures including RNA isolation, qPCR, protein isolation and Western Blot, independently after initial orientation and training in
the lab. Other responsibilities will include (but not limited to) maintaining multiple mouse lines, including breeding and genotyping, as well as overseeing animal experiments (weighing mice, transferring mice to ABSL2 facility, conducting running wheel experiments etc.). There will also be opportunities to learn
flowcytometry and viral titration etc. Some experience with rodents and other above-mentioned techniques will be viewed as an advantage but is not absolutely essential. We are happy to train up in all these areas as well!

Since the focus of our research is circadian biology-some experiments will require work at times outside of the usual hours of operation (9am-5pm) or over the weekends. Whenever such hours are needed, adjustments to the weekday hours will be made. Overall working hours and schedule are flexible based on the experimental needs. We are proud of our amazing teamwork and collaborations that makes science so much more fun! Based on general proficiency and interest, one may expect to take ownership of their own scientific
project. And as such, dedicated researchers will have ample opportunities for presenting their work at conference and eventually authorship in manuscripts. Further through the UPenn/CHOP campus one will have unparalleled access to lectures, seminar and workshops on a wide array of scientific topics.

The translational nature of the project would be a great opportunity for those seeking to build a career in biomedical research or medicine. This would an excellent opportunity for those taking time off prior to committing to a career in biomedical medicine/research to build up their cvs and gain hands-on experience in translational research on an exciting new field.

What you will do
Performs routine tests / experiments under the direction of principal investigator, supervisor or other designee
Performs research procedures on experimental samples as directed
Records and checks experiments/ results for completeness and accuracy
Performs calculations and maintains appropriate log and lab notebooks
Performs tasks that require familiarity with fundamental techniques and lab equipment
May assist with planning specific research protocols and procedures
Maintains office, lab area, solutions, reagents, supplies and equipment, disposes of specimens, media and other materials (using appropriate procedures)
Assists in care and maintenance of lab equipment
May coordinate schedules of tests and procedures
Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques
Records results, organizes data and maintains lab notebook in an organized manner
Compiles and helps analyze data, prepares charts, graphs, and results of studies as directed
Conducts literary searches as directed
Education Qualifications
High School Diploma / GED Required
Associate's Degree Preferred
Bachelor's Degree Preferred
Experience Qualifications
At least one (1) year of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Required
At least two (2) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Preferred
Skills and Abilities
Intermediate understanding of lab procedures, protocols, and equipment.
Basic exposure to lab specific experiments / techniques and scientific analysis
Excellent verbal and written communications skills
Excellent organizational skills
Solid critical thinking / problem-solving skills
Solid analytical skills

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must be fully vaccinated against COVID-19 and receive an annual influenza vaccine.

Employees may request exemptions for valid religious and medical reasons. Start dates may be delayed until candidates are immunized or exemption requests are reviewed.

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Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.